\'stem cell printing\' gets closer, as scientists use 3d technology to spit out human embryonic cells
by：QY Precision 2019-09-11
Author: Tanya Lewis published in \"Life Science\": 02/05/2015 11: 55 a. m. imagine if you can load living cells into a printer, then a 3D tissue can develop into a kidney or heart. Now scientists have developed the first printer for human embryonic stem cells, a step closer to this reality. In a new study, researchers from Heriot The University of Watt in Edinburgh, Scotland, has invented a cell printer that can spit out living embryonic stem cells. Printer can print uniform- The size of the cell droplets are light enough to maintain the vitality of the cell and to maintain its ability to develop into different cell types. New printing methods can be used to make 3D human tissues for testing new drugs, growing organs or eventually printing cells directly in the body. Human embryonic stem cells (hESCs) Obtained from human embryos, any cell type can be developed in adults, from brain tissue to muscles to bones. This attribute makes them ideal for use in regenerative medicine Repair, replace, and regenerate damaged cells, tissues, or organs. [ Stem cells: 5 interesting findings On a Laboratory plate, human embryonic stem cells can be placed in a solution containing biological clues that tell cells to develop into specific tissue types, a process called Division. This process begins with the formation of cells called \"pseudo-embryo bodies. \"Cell printers provide a way to produce an embryo body of a specific size and shape. In the new study, cell printers are made from improved CNC machines (a computer- Control Tools) Equipped with two \"creatures Ink dispenser: a stem cell containing nutrients A thick soup called cell culture medium and the other contains only culture medium. These embryonic stem cells are through computers. The operating valve, while the microscope installed on the printer provides the closure A view of what is being printed. Scientists use 3D printing to form aggregates of these embryonic stem cells, which are displayed within 24 hours (left)and 48 hours (right)after printing. The two inks are distributed in layers, one at the top of the other to produce cell droplets of different concentrations. There are only two nanometers in the small droplets, about five cells. These cells are printed on a plate containing many small wells. The plate is then flipped, so the drops are now hanging on top, allowing stem cells to form lumps in each hole. ( The printer places cells in precisely sized droplets and specific patterns, which is the best pattern for division. ) Tests showed that more than 95% of the cells were still alive after 24 hours of printing, indicating that they were not killed by the printing process. After three days, more than 89% of the cells were still alive and tested positive for their multiple markers They develop the potential for different cell types. Utkan Demirci, biomedical engineer at Harvard Medical School and the Brigham Women\'s Hospital, has done pioneering work in printing cells and believes the new research is moving in an exciting direction \"This technology may be very good for high-tech. Demirci told life science. People can build mini Using a repeatable, reliable approach, he says, to organize from the bottom up. It\'s a long time to build an entire organ. Demirci said, though he warned, \"it could be far from our goal today. \"Others created printers for other types of cells. Demirci and his colleagues made a machine to print mouse embryonic stem cells. Others have printed a human stem cell from a connecting tissue that cannot develop into the same number of cell types as embryonic stem cells. The researchers reported in the February that the current study was the first to print human embryonic stem cells. Journal of Biological processing Issue 5. Correction: A previous version of the story says researchers at the University of Edinburgh have developed the printer. In fact, they\'re from Herriot. University of Edinburgh Watt. Follow livesscience on Twitter @ livesscience. We are also on Facebook and Google.